Let’s start over…

Let's start over...

In 2006 Shinya Yamanaka, a japanese physician and researcher of adult stem cells, generated iPS cells from human adult fibroplasts. This breakthrough was a result of identifying the 4 key genes involved in reverting the specialised fibroplast cells to a more pluripotent state: Oct4, Sox2, Klf4 and c-Myc.

By using vector molecules to carry the extra DNA into the fibroplast, where they were switched on using chemical treatments or electrical impulses, they started to produce proteins that caused the cells to become iPS cells. From these iPS cells they were able to reprogram the cells into the three major tissue types from which all organs of the mammalian body are formed: ectoderm, mesoderm and endoderm.


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About annadyas

Currently reading 'The Epigenetics Revolution' and reguarly read the New Scientist, so most of my posts will be relating to what I have just read. Currently studying biology, chemistry, maths and psychology at A2, and am the president of my colleges biology society.

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